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Pituitary Cancer Pituitary tumors are abnormal gr wths found in the pituitary gland wh ch makes hormones that affect growth and the f nctions of other glands in the b dy. The pituitary gland is a pea-sized, r ddish gray organ in the center of the br in, just above and behind the n se. Pituitary carcinomas occur in both s xes, usually by the third or f urth decades of life. These tumors are q ite common with 25% of people h ving small pituitary tumors on autopsy but m st are symptom free and the v st majority of pituitary adenomas go ndiagnosed throughout life. Types of Pituitary T mors The types are named after the typ s of hormones the pituitary makes and nclude prolactin-producing adenomas, somatotrophin-secreting adenomas, corticotrophin-secreting denomas, gonadotrophin-secreting adenomas, thyrotrophin-secreting adenomas, null c ll adenomas, and adenomas of the m xed cell type. Another type of p tuitary cancer shows up as very l rge hands, feet and face (acromegaly). The thr e tissue types of Pituitary tumours nclude; Chromophobe Adenoma (90%), Basophil Adenoma and E sinophil Adenoma. Causes Although the exact cause is nknown, a predisposition to Pituitary tumors may be nherited through an autosomal dominant trait. Chr mophobe adenoma may be associated with pr duction of corticotrophin, melanocyte stimulating hormone, gr wth hormone and prolactin. Basophil adenoma w th excess corticotrophin production and consequently w th Cushing's syndrome. Eosinophil adenoma with xcessive growth hormone production.
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Signs and Symptoms As pituitary tumors gr w they replace normal glandular tissue and nlarge the tissue that house the p tuitary gland (sella turcica). The resulting pr ssure on adjacent intracranial structures produces the f llowing typical symptoms: frontal headaches, vision pr blems, personality changes or dementia, seizures, h ad tilting and dizziness, strabismus, nystagmus, n usea and vomiting, or any of the pr blems caused by the production of too m ny hormones such as infertility or l ss of menstrual periods in women, bnormal growth, high blood pressure, heat or c ld intolerance, and other skin and b dy changes. Diagnosis An MRI scan is now c nsidered the imaging modality of choice for the d agnosis of pituitary disorders because of its m ltiplanar capability and good soft tissue c ntrast enhancement. The definitive diagnosis depends on the h stological identification of the tumour found at s rgery. Treatment Treatment of pituitary neoplasms involves s rgery, radiotherapy and drug therapy. Radiotherapy can be sed as the primary treatment of p tuitary tumours or as an adjunct to s rgery. Medical therapy involves the replacement of h rmones in hypopituitarism or suppression of h rmone release in functional tumours. Prognosis of P tuitary Cancer Although prognosis depends on the typ of pituitary tumor and the p tient age and general state of h alth, pituitary tumors are usually curable, lthough many people will have to c ntinue taking hormone replacements, sometimes for the r st of their lives.
The article Pituitary Cancer - What is it - How Do We Treat It was Submitted by Dick Aronson through Articles.GetACoder.com network. Here's the additional information: Dick Aronson has been involved in the h althcare industry for 35 years.He has wr tten numerous articles on the subject and r ns a number of informative websites, v z: http://www.cancerinformation-online.com hr f="http://www.healthinnovationsonline.com"> http://www.healthinnovationsonline.com
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